An organoid library unveils subtype-specific IGF-1 dependency via a YAP–AP1 axis in human small cell lung cancer

已完结 10 由面条发布于 2025/10/30 15:38:44

DOI:10.1038/s43018-025-00945-y
作者：Takahiro Fukushima,?Kazuhiro Togasaki,?Junko Hamamoto,?Katsura Emoto,?Toshiki Ebisudani,?Akifumi Mitsuishi,?Kai Sugihara,?Taro Shinozaki,?Masahiko Okada,?Ayaka Saito,?Hatsuyo Takaoka,?Fumimaro Ito,?Li
文献类型：期刊论文
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Nature

Abstract：Small cell lung cancer (SCLC) is a devastating disease with limited therapeutic advancements. Although SCLC has recently been classified into four molecular subtypes, subtype-specific therap

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