β cell dedifferentiation, the underlying mechanism of diabetes in Wolfram syndrome

已完结 20 由 zhizhi 发布于 2025/11/24 20:12:18

DOI:10.1126/scitranslmed.adp2332
作者：Kikuko Amo-Shiinoki, Katsuya Tanabe, Wataru Nishimura, Masayuki Hatanaka, Manabu Kondo, Syota Kagawa, Meng Zou, Shuntaro Morikawa, Yoshihiko Sato, Mitsuhisa Komatsu, Hiroki Mizukami, Naoki Nishida, Sh
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Insulin-dependent diabetes in patients with Wolfram syndrome (WS; OMIM 222300) has been linked to endoplasmic reticulum (ER) stress caused by WFS1 gene mutations. However, the pathological p

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