In vivo self-assembled siRNAs ameliorate neurological pathology in TDP-43-associated neurodegenerative disease.

已取消 10 由方玮锋发布于 2025/11/18 20:52:57

DOI:10.1093/brain/awaf330
作者：Jianhao Wu,Jingwei Guo,Jiaxi Wu,Junzhu Song,Jiawei Xu,Yingqi Lin,Chunhui Huang,Chunxiang Shi,Jiawei Li,Caijuan Li,Yizhi Chen,Wei Wang,Jiale Gao,Qin Zhou,Yuanpei Zhang,Shihua Li,Xiao-Jiang Li,Chen-Yu Z
文献类型：期刊论文
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Oxford University Press

Abstract：Abnormal accumulation of TAR DNA-binding protein-43 (TDP-43) is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Small interfering RNAs (siRNAs

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