Structural insight into selectivity of amylin and calcitonin receptor agonists

已完结 10 由 cycq023 发布于 2025/6/30 16:25:25

DOI:10.1038/s41589-023-01393-4
作者：Jianjun Cao, Matthew J. Belousoff, Elliot Gerrard, Radostin Danev, Madeleine M. Fletcher, Emma Dal Maso, Herman Schreuder, Katrin Lorenz, Andreas Evers, Ga
文献类型：期刊论文
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Nature

Abstract：Amylin receptors (AMYRs), heterodimers of the calcitonin receptor (CTR) and one of three receptor activity-modifying proteins, are promising obesity targets. A hallmark of AMYR activation by

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