Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity

已完结 10 由 wei 发布于 2025/7/4 23:13:09

DOI:10.1016/j.cell.2025.06.004
作者：Jasper Du, Hui Chen, Jia You, Wei Hu, Jia Liu, Qiao Lu, Yong Zhang, Jie Gao, Meng-ju Lin, Connor James Ryan Foster, Eric Rao, Michael Cammer, Weiwei Yin, Shohei Koide, Catherine Pei-ju Lu, Wei Chen, J
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Therapeutically targeting pathogenic T cells in autoimmune diseases has been challenging. Although LAG-3, an inhibitory checkpoint receptor specifically expressed on activated T cells, is kn

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