Enzymatic synthesis of low molecular weight heparins from N-sulfo heparosan depolymerized by heparanase or heparin lyase

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DOI:10.1016/j.carbpol.2022.119825
作者：Yanlei Yu ,?Li Fu ,?Peng He ,?Ke Xia ,?Sony Varghese ,?Jonathan Dordick ,?Hong Wang ,?Fuming Zhang ,?Robert J. Linhardt
文献类型：期刊论文
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Elsevier

Abstract：Low-molecular-weight heparin (LMWH) is prepared from the controlled chemical or enzymatic depolymerization of animal sourced heparins. It has been widely used as an anticoagulant. Concerns a

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