Total neoadjuvant treatment with short-course radiotherapy followed by sintilimab plus capecitabine–oxaliplatin versus short-course radiotherapy followed by capecitabine–oxaliplatin in patients with locally advanced rectal cancer (SPRING-01): a single-centre, open-label, phase 2, randomised controlled trial

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DOI:10.1016/s1470-2045(25)00286-4
作者：Feng Tian, Honghai Dai, Dan Sha, Yuanzi Yu, Haiyan Jing, Cong Sun, Liang Shang, Yubo Liu, Renxiang Feng, Jun Li, Hongjun Liu, Yuezhi Chen, Yulong Shi, Jinshen Wang, Hongqing Zhuo, Xiaoqiao Zhang, Guod
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Abstract：BackgroundNeoadjuvant short-course radiotherapy combined with chemotherapy as total neoadjuvant therapy increases the pathological complete response rate for patients with locally advanced r

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