Synthesis of DNA-Encoded Macrocyclic Peptides via Nitrile-Aminothiol Click Reaction

已完结 10 由 5 发布于 2025/9/11 8:21:25

DOI:10.1021/acs.orglett.3c03284
作者：Lijun Fan*,&nbsp;Yang Yu*,&nbsp;Charles Jayne,&nbsp;John R. Frost and Jack D. Scott,&nbsp;
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：DNA-encoded library (DEL) technology holds exciting potential for discovering novel therapeutic macrocyclic peptides (MPs). Herein, we describe the development of a DEL-compatible peptide ma

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