TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

已完结 20 由 Folykiki 发布于 2025/9/10 16:30:48

DOI:10.1038/s41593-024-01610-w
作者：Edward N. Wilson,?Congcong Wang,?Michelle S. Swarovski,?Kristy A. Zera,?Hannah E. Ennerfelt,?Qian Wang,?Aisling Chaney,?Esha Gauba,?Javier A. Ramos Benitez,?Yann Le Guen,?Paras S. Minhas,?Maharshi Pan
文献类型：期刊论文
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Nature

Abstract：Human genetics implicate defective myeloid responses in the development of late-onset Alzheimer disease. A decline in peripheral and brain myeloid metabolism, triggering maladaptive immune r

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