Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance

已完结 20 由刘晓碟发布于 2025/9/27 20:01:41

DOI:10.1016/j.immuni.2025.07.013
作者：Yujia Wang, Yangyang Chai, Yanfang Liu, Xinpeng Liu, Yunkai Zhang, Zhen Yang, Shenhui Yin, Jianhua Luo, Zhiqing Li, Yan Gu, Yizhi Yu, Xuetao Cao
文献类型：期刊论文
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Abstract：Tumor cells’ macropinocytosis sustains their growth under nutrient-limiting conditions. However, the metabolic regulation of cancer macropinocytosis in immune escape and its effect on immuno

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