Design of soluble Notch agonists that drive T cell development and boost immunity

已完结 20 由 phyjun 发布于 2025/8/29 9:00:46

DOI:10.1016/j.cell.2025.07.009
作者：Rubul Mout, Ran Jing, Mayuri Tanaka-Yano, Emily D. Egan, Helen Eisenach, Martin A. Kononov, Roland Windisch, Mohamad Ali Toufic Najia, Allison Tompkins, Luca Hensch, Trevor Bingham, Rajesh Gunage, Yun
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Abstract：The rational design of receptor agonists to control cell signaling is an emerging strategy for developing disease therapeutics. Creating a soluble cytokine-like agonist for the Notch recepto

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