CHIP protects lysosomes from CLN4 mutant-induced membrane damage

已完结 10 由 Calor 发布于 2025/9/4 9:10:19

DOI:10.1038/s41556-025-01738-2
作者：Juhyung Lee, Natalie Chin, Jizhong Zou, Wan Nur Atiqah Binti Mazli, Michal Jarnik, Layla Saidi, Yue Xu, Eutteum Jeong, Jessica Suh, John Replogle, Michael E. Ward, Juan S. Bonifacino, Wei Zheng, Ling
文献类型：期刊论文
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Nature

Abstract：Understanding how cells mitigate lysosomal damage is critical for unravelling pathogenic mechanisms of lysosome-related diseases. Here we generate and characterize induced pluripotent stem c

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