Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles

已完结 10 由 Josephina 发布于 2025/9/3 17:12:04

DOI:10.1021/acsnano.2c10936
作者：Yulin Mo,?Miffy H. Y. Cheng,?Andrew D’Elia,?Katie Doran,?Lili Ding,?Juan Chen*,?Pieter R. Cullis and Gang Zheng*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Lipid nanoparticles (LNPs) have achieved clinical success in delivering small interfering RNAs (siRNAs) for targeted gene therapy. However, endosomal escape of siRNA into the cytosol remains

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