A catalytic alkene insertion approach to bicyclo[2.1.1]hexane bioisosteres

已完结 10 由 mk 发布于 2025/5/1 22:25:19

DOI:10.1038/s41557-023-01135-y
作者：Soumitra Agasti, Frédéric Beltran, Emma Pye, Nikolas Kaltsoyannis, Giacomo E. M. Crisenza, David J. Procter
文献类型：期刊论文
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Nature

Abstract：C(sp3)-rich bicyclic hydrocarbon scaffolds, as exemplified by bicyclo[1.1.1]pentanes, play an increasingly high-profile role as saturated bioisosteres of benzenoids in medicinal chemistry an

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