Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage

已完结 10 由谢女士发布于 2025/3/30 19:40:59

DOI:10.1038/s41587-025-02570-7
作者：Zachary R. Baker, Yao Zhang, Haiyan Zhang, Hollyn C. Franklin, Priscila B. S. Serpa, Teresa Southard, Liwu Li, Bryan B. Hsu
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Oral administration of biologic drugs is challenging because of the degradative activity of the upper gastrointestinal tract. Strategies that use engineered microbes to produce biologics in

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