Inhibition of USP7 enhances CD8+ T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation

已完结 10 由 sifs 发布于 2025/5/20 11:16:59

DOI:10.1038/s41401-024-01263-2
作者：Lin-lin Sun, Li-na Zhao, Jiao Sun, Hong-feng Yuan, Yu-fei Wang, Chun-yu Hou, Pan Lv, Hui-hui Zhang, Guang Yang, Ning-ning Zhang, Xiao-dong Zhang, Wei Lu
文献类型：期刊论文
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Springer

Abstract：Lymphocyte activation gene 3 (LAG3), an immune checkpoint molecule expressed on activated T cells, functions as a negative regulator of immune responses. Persistent antigen exposure in the t

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