Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase.

已完结 10 由 rui 发布于 2025/5/26 16:17:44

DOI:10.1126/science.adt5199
作者：Isaac P Witte,?George D Lampe,?Simon Eitzinger,?Shannon M Miller,?Kiara N Berríos,?Amber N McElroy,?Rebeca T King,?Olivia G Stringham,?Diego R Gelsinger,?Phuc Leo H Vo,?Albert T Chen,?Jakub Tolar,?Ma
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Abstract：Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life scien

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