Development of [68Ga]Ga/[177Lu]Lu-DOTA-NI-FAPI-04 Containing a Nitroimidazole Moiety as New FAPI Radiotracers with Improved Tumor Uptake and Retention

已完结 10 由 Luke 发布于 2025/1/16 17:01:45

DOI:10.1021/acs.jmedchem.4c02015
作者：Yang Luo, Wenbin Jin, Jie Zang, Guochang Wang, Lin Zhu, Hank F. Kung
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Fibroblast activation protein (FAP), which is overexpressed in cancer-associated fibroblasts (CAFs), represents a promising target for cancer diagnosis and therapy. Hypoxia is a common featu

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