A Dual-Target and Dual-Mechanism Design Strategy by Combining Inhibition and Degradation Together

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DOI:10.1021/jacs.4c11930
作者：Yongbo Liu, Xiuyun Sun, Qianlong Liu, Chi Han, Yu Rao
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Glioblastoma, a highly aggressive brain tumor, lacks effective treatment with low 5 year survival rates. Urgency for new therapies is evident. Mammalian targets of rapamycin (mTOR) and G1 to

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