RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

已完结 10 由钱钱发布于 2025/3/13 10:53:28

DOI:10.1038/s41586-024-08508-4
作者：Zachary Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson, Jayon Lihm, George Payne, Olga Lyudovyk, Luis A. Rojas, Nan Pang, Akihiro Ohmoto, Masataka Amisaki,
文献类型：期刊论文
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Nature

Abstract：A fundamental challenge for cancer vaccines is to generate long-lived functional T cells that are specific for tumour antigens. Here we find that mRNA–lipoplex vaccines against somatic mutat

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