Computational design of serine hydrolases

已完结 10 由 phyjun 发布于 2025/2/17 13:58:21

DOI:10.1126/science.adu2454
作者：Anna Lauko, Samuel J. Pellock, Kiera H. Sumida, Ivan Anishchenko, David Juergens, Woody Ahern, Jihun Jeung, Alex Shida, Andrew Hunt, Indrek Kalvet, Christoffer Norn, Ian R. Humphreys, Cooper Jamieson,
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：The design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabi

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