Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 2: Synthesis of the Payload, Linker, and Drug Linker

已完结 10 由北菜的豆发布于 2024/9/20 23:09:58

DOI:10.1021/acs.oprd.4c00318
作者：Katherine Payne, Jeremy C. Tran, Brooke Gill, William Guy, Caitlyn McNichol, Kareem Bdeir, Malcolm Reider, Andrea Stair, Lorenzo Pontini, Gabriele Cerai, Jacopo Roletto, Aaron M. Whittaker
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：The discovery of novel auristatin-derived antibody drug conjugates (ADCs) with attenuated bystander activity is an area of intense research. Recently, drug-linker SGD-9501-TFA emerged as a p

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