DNA-binding-domain fusions enhance the targeting range and precision of Cas9

已完结 10 由 zxh 发布于 2024/10/7 22:00:56

DOI:10.1038/nmeth.3624
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/nmeth.3624

Nature

Abstract：Fusing a DNA-binding domain to Cas9 with an attenuated, more promiscuous PAM-recognition domain increases the targeting range of Cas9 as well as its specificity. The CRISPR-Cas9 system is co

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