Branched chemically modified poly(A) tails enhance the translation capacity of mRNA.

已完结 10 由钱钱发布于 2024/7/31 16:05:19

DOI:10.1038/s41587-024-02174-7
作者：Hongyu Chen, Dangliang Liu, Jianting Guo, Abhishek Aditham, Yiming Zhou, Jiakun Tian, Shuchen Luo, Jingyi Ren, Alvin Hsu, Jiahao Huang, Franklin Kostas, Mingrui Wu, David R Liu, Xiao Wang
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41587-024-02174-7

Nature

Abstract：Although messenger RNA (mRNA) has proved effective as a vaccine, its potential as a general therapeutic modality is limited by its instability and low translation capacity. To increase the d

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