Synthesis of Lenacapavir Sodium: Active Pharmaceutical Ingredient Process Development and Scale-up

已完结 10 由北菜的豆发布于 2024/8/5 21:46:14

DOI:10.1021/acs.oprd.4c00242
作者：Anna M. Wagner, Sara A. Bonderoff, Stanley Chang, Jeffrey Deignan, Michelle M. Esanu, Huy Van Huynh, Tianmin Niu, Vinh Ngo, B. Michael O’Keefe, Jenny Phoenix, Trevor J. Rainey, Benjamin J. Roberts, Jinyu Shen, Craig Stewart, Amanda L. Vandehey, Scott A. Wolckenhauer, Chloe Y. Wong, Brian H. Yarmuch
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Lenacapavir sodium (GS-6207-02) is a first-in-class HIV capsid inhibitor. Process development of the four-step final assembly of lenacapavir sodium from four synthetic intermediates is descr

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