Raloxifene-driven benzothiophene derivatives: Discovery, structural refinement, and biological evaluation as potent PPARγ modulators based on drug repurposing

已完结 10 由纯情无敌霹雳牛马发布于 2024/8/3 23:11:58

DOI:10.1016/j.ejmech.2024.116325
文献类型：期刊论文
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Elsevier

Abstract：By virtue of the drug repurposing strategy, the anti-osteoporosis drug raloxifene was identified as a novel PPARγ ligand through structure-based virtual high throughput screening (SB-VHTS) o

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