Discovery of an enantiopure N-[2-hydroxy-3-phenyl piperazine propyl]-aromatic carboxamide derivative as highly selective α1D/1A-adrenoceptor antagonist and homology modelling

已完结 10 由纯情无敌霹雳牛马发布于 2024/8/3 23:14:00

DOI:10.1016/j.cclet.2024.109594
作者：Junjun Huang, Ran Chen, Yajian Huang, Hang Zhang, Anran Zheng, Qing Xiao, Dan Wu, Ruxia Duan, Zhi Zhou, Fei He, Wei Yi
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.cclet.2024.109594

Elsevier

Abstract：α1-Adrenergic receptor (AR) blockers can be effective for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS), their usage is limited by cardiovascular-rela

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