Radiotherapy-triggered reduction of platinum-based chemotherapeutic prodrugs in tumours.

已完结 10 由 rrrr 发布于 2024/8/19 14:36:19

DOI:10.1038/s41551-024-01239-x
作者：Qunfeng Fu, Shuren Zhang, Siyong Shen, Zhi Gu, Junyi Chen, Dongfan Song, Pengwei Sun, Chunhong Wang, Zhibin Guo, Yunlong Xiao, Yi Qin Gao, Zijian Guo, Zhibo Liu
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41551-024-01239-x

Nature

Abstract：Pt(II) drugs are a widely used chemotherapeutic, yet their side effects can be severe. Here we show that the radiation-induced reduction of Pt(IV) complexes to cytotoxic Pt(II) drugs is rapi

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