Acid-degradable lipid nanoparticles enhance the delivery of mRNA

已完结 10 由 1236544 发布于 2024/8/24 22:58:11

DOI:10.1038/s41565-024-01765-4
作者：Sheng Zhao, Kewa Gao, Hesong Han, Michael Stenzel, Boyan Yin, Hengyue Song, Atip Lawanprasert, Josefine Eils? Nielsen, Rohit Sharma, Opeyemi H. Arogundade, Sopida Pimcharoen, Yu-Ju Chen, Abhik Paul, J
文献类型：期刊论文
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Abstract：Lipid nanoparticle (LNP)–mRNA complexes are transforming medicine. However, the medical applications of LNPs are limited by their low endosomal disruption rates, high toxicity and long tissu

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