Step-Economic Synthesis of Tamsulosin Hydrochloride via Continuous Chlorosulfonation and Biocatalytic Transamination

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DOI:10.1021/acs.oprd.4c00236
作者：ágnes Malta-Lakó, Raquel M. Dur?o, László Poppe, Ricardo F. Mendon?a
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：A new process was developed for the synthesis of (R)-tamsulosin in 4 chemical steps from readily available 4-methoxyphenylacetone using continuous chlorosulfonation and biocatalysis. Several

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