Individualized Antisense Oligonucleotide Therapies: How to Approach the Challenge of Manufacturing These Oligos from a Chemistry, Manufacturing, and Control-Regulatory Standpoint.

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DOI:10.1089/nat.2021.0030
作者：Marc M Lemaitre
文献类型：期刊论文
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Abstract：With the development of antisense oligonucleotides over more than 30 years and the increasing number of identified unique severely debilitating or life-threatening diseases affecting only 1

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