Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy

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DOI:10.1126/science.adl4492
作者：Tae Gun Kang, Xin Lan, Tian Mi, Hongfeng Chen, Shanta Alli, Song-Eun Lim, Sheetal Bhatara, Anoop Babu Vasandan, Grace Ward, Sofia Bentivegna, Josh Jan
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Epigenetic reinforcement of T cell exhaustion is known to be a major barrier limiting T cell responses during immunotherapy. However, the core epigenetic regulators restricting antitumor imm

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