Engineered Cas13 variants with minimal collateral RNA targeting

求助中 10 由 limi 发布于 2024/10/30 9:30:29

DOI:10.1038/s41587-022-01423-x
文献类型：期刊论文
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Nature

Abstract：The application of CRISPR–Cas13 for targeted RNA degradation is hindered by the existence of collateral effects induced by Cas13. We screened hundreds of engineered Cas13 variants using a co

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