Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles

已完结 10 由 1236544 发布于 2024/2/25 10:52:03

DOI:10.1021/acsnano.2c10936
作者：Yulin Mo, Miffy H. Y. Cheng, Andrew D’Elia, Katie Doran, Lili Ding, Juan Chen*, Pieter R. Cullis and Gang Zheng*,
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Lipid nanoparticles (LNPs) have achieved clinical success in delivering small interfering RNAs (siRNAs) for targeted gene therapy. However, endosomal escape of siRNA into the cytosol remains

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