Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming.

已完结 10 由 han 发布于 2024/4/1 11:59:52

DOI:10.1038/s43018-024-00748-7
作者：Xujia Wu, Huairui Yuan, Qiulian Wu, Yixin Gao, Tingting Duan, Kailin Yang, Tengfei Huang, Shuai Wang, Fanen Yuan, Derrick Lee, Suchet Taori, Tritan Plute, Søren Heissel, Hanan Alwaseem, Michael Isay-Del Viscio, Henrik Molina, Sameer Agnihotri, Dennis J Hsu, Nu Zhang, Jeremy N Rich
文献类型：期刊论文
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Nature

Abstract：Cancers commonly reprogram translation and metabolism, but little is known about how these two features coordinate in cancer stem cells. Here we show that glioblastoma stem cells (GSCs) disp

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