在尼日利亚高原州应用心理和教育健康模型来确定药剂师主导的认知和行为干预对结核病治疗结果的影响。

Comfort Nanbam Sariem, Maxwell Patrick Dapar, Nenman Musa Lenka, Jacob Kolawole, John Aguiyi
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引用次数: 0

摘要

背景:结核病(TB)的长期多药治疗方案可能导致不依从性和不成功的治疗结果。教育和心理健康模型可用于设计认知和行为干预措施,以改善依从性和治疗结果。目的:探讨认知和行为干预对结核病治疗效果的影响。方法:在6个结核病治疗中心进行了准实验研究,包括强化药物教育和依从性咨询(MEAC),从结构化的有效心理测量量表设计。在强化治疗和继续治疗阶段,从463名结核病患者(对照组232人,干预组231人)中收集了三次不同时间的数据。比较两组患者的基线人口学特征和临床特征。通过确定治疗成功是否与认知和行为干预以及药物依从性相关,使用广义估计方程模型来分析重复测量。结果:男性290例(62.6%)。平均年龄36.75±13.9岁。大多数结核病患者为新诊断者413例(89.2%),HIV阴性者315例(68%),中等文化程度者216例(46.6%)。两组间基线特征无显著差异。干预组治疗成功的可能性是干预组的四倍(结论:对结核病患者进行认知和行为干预改善了成功的治疗结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Applying Psychological and Educational Health Models to Determine the Effect of a Pharmacist-led Cognitive and Behavioral Intervention on Tuberculosis Treatment Outcomes in Plateau State, Nigeria.

Applying Psychological and Educational Health Models to Determine the Effect of a Pharmacist-led Cognitive and Behavioral Intervention on Tuberculosis Treatment Outcomes in Plateau State, Nigeria.

Applying Psychological and Educational Health Models to Determine the Effect of a Pharmacist-led Cognitive and Behavioral Intervention on Tuberculosis Treatment Outcomes in Plateau State, Nigeria.

Background: The prolonged multi-drug treatment regimen for tuberculosis (TB) can lead to non-adherence and unsuccessful treatment outcomes. Educational and psychological health models can be used to design cognitive and behavioral interventions to improve adherence and treatment outcomes. Objective: To determine the effect of cognitive and behavioral interventions on TB treatment outcomes. Methods: The quasi-experimental study conducted in six TB treatment centers involved reinforced medication education and adherence counseling (MEAC), designed from a structured validated psychometric scale. Data were collected three different times during the intensive and continuation phases of treatment from 463 TB patients (232 in the control and 231 in the intervention group). Baseline demographic and clinical characteristics were compared between the groups. The generalized estimating equation model was used to analyze the repeated measures by determining if treatment success was associated with the cognitive and behavioral interventions and medication adherence. Results: The males made up 290(62.6 %) of the population. The mean age was 36.75±13.9. Most of the TB patients were newly diagnosed 413(89.2%) and HIV negative 315(68%), with secondary level of education 216(46.6%). There was no significant difference in baseline characteristics between the groups. The intervention group was four times more likely to have treatment success (p<0.01; CI=1.5-8.4), compared to the control group. Medication-adherent TB patients were 24 times more likely to have treatment success than patients who did not adhere (p<0.001; 10.8-52.1). TB patients' emotions, attitudes, and perceptions of their medicines were predictors of treatment success (p<0.05; 1.0 - 1.1). Conclusion: The cognitive and behavioral interventions administered to TB patients improved successful treatment outcomes.

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