主动脉瓣再植术修复及维持关节定向的效果。

IF 3.3 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
John J Kelly, Nimesh D Desai, William L Patrick, Brittany J Cannon, Yu Zhao, Selim Mosbahi, Mikolaj Berezowksi, Amit Iyengar, Wilson Y Szeto, Joseph E Bavaria
{"title":"主动脉瓣再植术修复及维持关节定向的效果。","authors":"John J Kelly,&nbsp;Nimesh D Desai,&nbsp;William L Patrick,&nbsp;Brittany J Cannon,&nbsp;Yu Zhao,&nbsp;Selim Mosbahi,&nbsp;Mikolaj Berezowksi,&nbsp;Amit Iyengar,&nbsp;Wilson Y Szeto,&nbsp;Joseph E Bavaria","doi":"10.21037/acs-2023-avs2-18","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°-180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°-150° orientation.</p><p><strong>Methods: </strong>A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°-150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival.</p><p><strong>Results: </strong>The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0-17.2%), 7.1% (0-19.7%), and 5.3% (0.3-22%), respectively. There was no mortality for the entire duration of the study period.</p><p><strong>Conclusions: </strong>This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required.</p>","PeriodicalId":8067,"journal":{"name":"Annals of cardiothoracic surgery","volume":"12 4","pages":"318-325"},"PeriodicalIF":3.3000,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/ef/acs-12-04-318.PMC10405331.pdf","citationCount":"0","resultStr":"{\"title\":\"Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation.\",\"authors\":\"John J Kelly,&nbsp;Nimesh D Desai,&nbsp;William L Patrick,&nbsp;Brittany J Cannon,&nbsp;Yu Zhao,&nbsp;Selim Mosbahi,&nbsp;Mikolaj Berezowksi,&nbsp;Amit Iyengar,&nbsp;Wilson Y Szeto,&nbsp;Joseph E Bavaria\",\"doi\":\"10.21037/acs-2023-avs2-18\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°-180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°-150° orientation.</p><p><strong>Methods: </strong>A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°-150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival.</p><p><strong>Results: </strong>The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0-17.2%), 7.1% (0-19.7%), and 5.3% (0.3-22%), respectively. There was no mortality for the entire duration of the study period.</p><p><strong>Conclusions: </strong>This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required.</p>\",\"PeriodicalId\":8067,\"journal\":{\"name\":\"Annals of cardiothoracic surgery\",\"volume\":\"12 4\",\"pages\":\"318-325\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2023-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/ef/acs-12-04-318.PMC10405331.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of cardiothoracic surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21037/acs-2023-avs2-18\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of cardiothoracic surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/acs-2023-avs2-18","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

背景:对于非常不对称的双尖瓣主动脉瓣(BAV),是否应该完成保留瓣根再植(VSRR),以保留原关节的不对称取向,或者是否应该使其对称(180°-180°),争论仍然存在。在此,我们提出了我们的方法,其中保留了原有的不对称性,并将瓣膜重新植入210°-150°方向。方法:回顾性分析2004年1月1日至2023年3月1日在同一医院接受VSRR治疗的130例BAV患者。其中37例不对称移植(210°-150°)。主要结局为>中度主动脉不全(AI)。次要结局包括严重主动脉瓣狭窄(AS)、再干预和生存。结果:37例患者以男性居多[94.6%(35/37)],平均年龄46.3岁,合并症发生率低。40.5%(15/37)的患者在手术前至少存在中度AI。本组病例均为Sievers 1型,平均相交角为128.2°。81.1%(30/37)需要小叶修复,最常见的是连体尖中央应用[96.7%(29/30)]和中缝松解[73.3%(22/30)]。没有30天死亡率或中风。10年时,>中度AI、重度AS和再干预的累积发生率分别为7.6%(0-17.2%)、7.1%(0-19.7%)和5.3%(0.3-22%)。在整个研究期间没有死亡率。结论:该系列研究表明,在不对称BAV再植手术中,保持关节朝向的10年预后良好。然而,需要更多患者的进一步研究,更长的随访时间,并直接比较相似BAV形态的对称再植。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation.

Background: Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°-180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°-150° orientation.

Methods: A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°-150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival.

Results: The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0-17.2%), 7.1% (0-19.7%), and 5.3% (0.3-22%), respectively. There was no mortality for the entire duration of the study period.

Conclusions: This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.60
自引率
0.00%
发文量
58
期刊介绍: Information not localized
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信