[儿童肥胖与阻塞性睡眠呼吸暂停相关性研究进展]。

Q4 Medicine
Jing Li, Quyang Yang, Ying Xu, Fugen Han, Jing Zhao
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引用次数: 1

摘要

儿童肥胖的患病率正在逐渐上升,全球女孩和男孩的肥胖率分别达到5.6%和7.8%。这也导致肥胖相关疾病的患病率相应增加,尤其是那些涉及阻塞性睡眠呼吸暂停(OSA)的疾病。肥胖是儿童OSA的独立危险因素和调节因子。OSA与儿童肥胖之间存在双向因果关系。OSA与肥胖之间的关联因素包括全身炎症、氧化应激和肠道微生物群等。然而,肥胖相关炎症状态与OSA发病机制之间的因果关系仍需适当证实。本综述旨在调查儿童肥胖与OSA之间的联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progress on correlation between childhood obesity and obstructive sleep apnea].

Prevalence of childhood obesity is progressively increasing, reaching worldwide levels of 5.6% in girls and of 7.8% in boys. This also leads to a corresponding increase in the prevalence of obesity-associated morbidities particularly those involving obstructive sleep apnea(OSA). Obesity is an independent risk factor and regulator of OSA in children. There is a bidirectional causal relationship between OSA and obesity in children. The factors involved in the association between OSA and obesity are systemic inflammation, oxidative stress, and gut microbiota etc. However, a causal link between obesity-related inflammatory state and OSA pathogenesis still needs to be properly confirmed. The present review aimed to investigate the links between childhood obesity and OSA.

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