[经鼻内窥镜全上颌骨切除术治疗鼻窦腺样囊性癌的疗效]。

Q4 Medicine
Quan Liu, Yuting Lai, Jingyi Yang, Huankang Zhang, Xicai Sun, Yurong Gu, Houyong Li, Hongmeng Yu, Dehui Wang
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引用次数: 0

摘要

目的:评估经鼻内镜全上颌骨切除术治疗鼻窦腺样囊性癌侵犯硬腭的预后。方法:回顾性分析2014年5月至2020年12月期间通过经鼻内镜全上颌骨切除术治疗的26例鼻窦腺样囊性癌侵犯硬腭的患者的临床数据。采用Kaplan-Meier法分析生存率、局部复发和远处转移。采用Cox回归法研究预后因素。上颌骨切除术后的咀嚼功能也通过患者咀嚼功能满意度问卷进行了评估。结果:8例患者的边缘(30%)为阳性。为阳性。中位随访时间为38个月(6至85个月)。25名患者复发。4名患者死于远处转移。5年总生存率和无复发生存率分别为79.5%和89.1%。多变量分析显示,阳性边缘(P=0.018)、复发(P=0.006)和远处转移(P=0.007)是预测结果的独立因素。和远处转移(P=0.04)。结论:经鼻内镜全上颌骨切除术可用于治疗硬腭侵犯的鼻窦腺样囊性癌。阳性边缘、局部复发和远处转移是预测患者预后的重要指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The outcome of transnasal endoscopic total maxillectomy in the treatment of sinonasal adenoid cystic carcinoma].

Objective:To assess the prognosis of sinonasal adenoid cystic carcinoma with hard palatine invasion treated by transnasal endoscopic total maxillectomy. Methods:Clinical data of twenty-six patients with sinonasal adenoid cystic carcinoma invading hard palatine treated by transnasal endoscopic total maxillectomy between May 2014 and December 2020 was analyzed retrospectively. Survival rate, local recurrence and distant metastasis were analyzed using Kaplan-Meier method. Cox regression was used to investigate the prognosis factors. Masticatory function after maxillectomy has also been assessed using the questionnaire of patients' satisfaction about masticatory function. Results:Margins in 8 patients(30%) were positive. The median time of follow-up was 38 months(6 to 85 months). Twenty-five patients recurred. Four patients died of distant metastasis. The 5-year overall survival rate and relapse-free survival rate was 79.5% and 89.1%, respectively. Independent predictors of outcome on multivariate analysis were positive margin(P=0.018), recurrence(P=0.006) and distant metastasis(P=0.04). Conclusion:Transnasal endoscopic total maxillectomy could be performed for the treatment of the sinonasal adenoid cystic carcinoma with hard palatine invasion. Positive margin, local recurrence and distant metastasis were important predictors for patients' prognosis.

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