全国肺栓塞相关死亡率的性别、种族和地理差异。

IF 6.8 2区 医学 Q1 RESPIRATORY SYSTEM
Mohamed Zghouzi, Hunter Mwansa, Supriya Shore, Syed Nabeel Hyder, Neil Kamdar, Victor M Moles, Geoffrey D Barnes, James Froehlich, Vallerie V McLaughlin, Timir K Paul, Kenneth Rosenfield, Jay Giri, Brahmajee K Nallamothu, Vikas Aggarwal
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引用次数: 1

摘要

理由:急性肺栓塞是心血管死亡的主要原因。关于全国肺栓塞死亡率趋势的数据有限。了解这些趋势对于解决与肺栓塞相关的死亡率和相关差异至关重要。目的:分析与急性肺栓塞相关的全国死亡率趋势,确定研究期间每100000人的总年龄调整死亡率(AAMR),并评估不同性别、种族和地理位置的AAMR变化。方法:我们使用15岁个体的死亡率数据进行了回顾性队列分析 2006年1月至2019年12月,疾病控制和预防中心流行病研究数据库中列出了肺栓塞作为潜在死亡原因的年数。这些数据由国家卫生统计中心提供。结果:2006年至2019年间,全国共有109992例肺栓塞相关死亡病例。其中,女性占60113人(54.7%)。每100000人的AAMR没有显著变化,从2006年的2.84变化到2019年的2.81(平均年百分比变化[APC],0.2;95%置信区间[CI],-0.1-0.5;P = 0.15)。在整个研究期间,男性的AAMR比女性增加(AAPC,男性0.7;95%置信区间,0.3-1.2;P = 0.004对AAPC,女性为-0.4;95%置信区间,-1.1至0.3;P = 0.23)。同样,与白人相比,黑人肺栓塞的AAMR从5.18增加到5.26(AAPC,0.4;95%CI,0.0到0.7;P = 0.05)和2.82至2.86(AAPC,0.0;95%置信区间,-0.6至0.6;P = 0.99)。同样,在研究期间,农村地区的肺栓塞AAMR高于微型城市和大城市地区(分别为4.07[95%CI,4.02至4.12]对3.24[95%CI、3.21至3.27]对2.32[9%CI,2.30-2.34])。结论:在过去的十年中,肺栓塞的死亡率仍然很高且没有变化,肺栓塞患者的性别、种族和社会经济差异仍然存在。需要有针对性地努力降低肺栓塞死亡率并解决这种差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sex, Racial, and Geographic Disparities in Pulmonary Embolism-related Mortality Nationwide.

Rationale: Acute pulmonary embolism is a leading cause of cardiovascular death. There are limited data on the national mortality trends from pulmonary embolism. Understanding these trends is crucial for addressing the mortality and associated disparities associated with pulmonary embolism. Objectives: To analyze the national mortality trends related to acute pulmonary embolism and determine the overall age-adjusted mortality rate (AAMR) per 100,000 population for the study period and assess changes in AAMR among different sexes, races, and geographic locations. Methods: We conducted a retrospective cohort analysis using mortality data of individuals aged ⩾15 years with pulmonary embolism listed as the underlying cause of death in the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database from January 2006 to December 2019. These data are produced by the National Center for Health Statistics. Results: A total of 109,992 pulmonary embolism-related deaths were noted in this dataset nationwide between 2006 and 2019. Of these, women constituted 60,113 (54.7%). The AAMR per 100,000 was not significantly changed, from 2.84 in 2006 to 2.81 in 2019 (average annual percentage change [AAPC], 0.2; 95% confidence interval [CI], -0.1 to 0.5; P = 0.15). AAMR increased for men throughout the study period compared with women (AAPC, 0.7 for men; 95% CI, 0.3 to 1.2; P = 0.004 vs. AAPC, -0.4 for women; 95% CI, -1.1 to 0.3; P = 0.23, respectively). Similarly, AAMR for pulmonary embolism increased for Black compared with White individuals, from 5.18 to 5.26 (AAPC, 0.4; 95% CI, 0.0 to 0.7; P = 0.05) and 2.82 to 2.86 (AAPC, 0.0; 95% CI, -0.6 to 0.6; P = 0.99), respectively. Similarly, AAMR for pulmonary embolism was higher in rural areas than in micropolitan and large metropolitan areas during the study period (4.07 [95% CI, 4.02 to 4.12] vs. 3.24 [95% CI, 3.21 to 3.27] vs. 2.32 [95% CI, 2.30-2.34], respectively). Conclusions: Pulmonary embolism mortality remains high and unchanged over the past decade, and enduring sex, racial and socioeconomic disparities persist in pulmonary embolism. Targeted efforts to decrease pulmonary embolism mortality and address such disparities are needed.

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来源期刊
Annals of the American Thoracic Society
Annals of the American Thoracic Society Medicine-Pulmonary and Respiratory Medicine
CiteScore
9.30
自引率
3.60%
发文量
0
期刊介绍: The Annals of the American Thoracic Society (AnnalsATS) is the official international online journal of the American Thoracic Society. Formerly known as PATS, it provides comprehensive and authoritative coverage of a wide range of topics in adult and pediatric pulmonary medicine, respiratory sleep medicine, and adult medical critical care. As a leading journal in its field, AnnalsATS offers up-to-date and reliable information that is directly applicable to clinical practice. It serves as a valuable resource for clinical specialists, supporting their formative and continuing education. Additionally, the journal is committed to promoting public health by publishing research and articles that contribute to the advancement of knowledge in these fields.
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