Carmen Lobo Rodríguez , Ana M. López-Calleja , Paloma Morales de los Ríos Luna , Susana Sánchez Vázquez , Ángela Molinero Sampedro , Amparo López-Esteban
{"title":"SARS-COV-2冠状病毒大流行第一波与第六波在免疫介导性疾病患者中的比较","authors":"Carmen Lobo Rodríguez , Ana M. López-Calleja , Paloma Morales de los Ríos Luna , Susana Sánchez Vázquez , Ángela Molinero Sampedro , Amparo López-Esteban","doi":"10.1016/j.reumae.2023.02.011","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p><span>Recent evidence shows that COVID-19 infection does not have a worse prognosis in patients with immune-mediated </span>inflammatory diseases (IMID), although they develop a worse response to vaccination.</p></div><div><h3>Objective</h3><p>To compare the incidence of COVID-19 and clinical features in patients with IMID between the first and sixth waves.</p></div><div><h3>Method</h3><p>Prospective observational study of two cohorts of IMID patients diagnosed with COVID-19. First cohort March to May 2020, and second cohort December/2021 to February/2022.</p><p>Sociodemographic and clinical variables were collected and, in the second cohort, COVID-19 vaccination status. Statistical analysis established differences in characteristics and clinical course between the two cohorts.</p></div><div><h3>Results</h3><p><span>In total, 1627 patients were followed up, of whom 77 (4.60%) contracted COVID-19 during the first wave and 184 in the sixth wave (11.3%). In the sixth wave, there were fewer hospitalisations, intensive care unit admissions, and deaths than in the first wave (</span><em>p</em> <!-->=<!--> <!-->.000) and 180 patients (97.8%) had at least one dose of vaccine.</p></div><div><h3>Conclusion</h3><p>Early detection and vaccination have prevented the occurrence of serious complications.</p></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"19 9","pages":"Pages 507-511"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Comparison of the first and sixth waves of the SARS-COV-2 coronavirus pandemic in patients with immune-mediated disease\",\"authors\":\"Carmen Lobo Rodríguez , Ana M. López-Calleja , Paloma Morales de los Ríos Luna , Susana Sánchez Vázquez , Ángela Molinero Sampedro , Amparo López-Esteban\",\"doi\":\"10.1016/j.reumae.2023.02.011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p><span>Recent evidence shows that COVID-19 infection does not have a worse prognosis in patients with immune-mediated </span>inflammatory diseases (IMID), although they develop a worse response to vaccination.</p></div><div><h3>Objective</h3><p>To compare the incidence of COVID-19 and clinical features in patients with IMID between the first and sixth waves.</p></div><div><h3>Method</h3><p>Prospective observational study of two cohorts of IMID patients diagnosed with COVID-19. First cohort March to May 2020, and second cohort December/2021 to February/2022.</p><p>Sociodemographic and clinical variables were collected and, in the second cohort, COVID-19 vaccination status. Statistical analysis established differences in characteristics and clinical course between the two cohorts.</p></div><div><h3>Results</h3><p><span>In total, 1627 patients were followed up, of whom 77 (4.60%) contracted COVID-19 during the first wave and 184 in the sixth wave (11.3%). In the sixth wave, there were fewer hospitalisations, intensive care unit admissions, and deaths than in the first wave (</span><em>p</em> <!-->=<!--> <!-->.000) and 180 patients (97.8%) had at least one dose of vaccine.</p></div><div><h3>Conclusion</h3><p>Early detection and vaccination have prevented the occurrence of serious complications.</p></div>\",\"PeriodicalId\":94193,\"journal\":{\"name\":\"Reumatologia clinica\",\"volume\":\"19 9\",\"pages\":\"Pages 507-511\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Reumatologia clinica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2173574323001107\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reumatologia clinica","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2173574323001107","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of the first and sixth waves of the SARS-COV-2 coronavirus pandemic in patients with immune-mediated disease
Introduction
Recent evidence shows that COVID-19 infection does not have a worse prognosis in patients with immune-mediated inflammatory diseases (IMID), although they develop a worse response to vaccination.
Objective
To compare the incidence of COVID-19 and clinical features in patients with IMID between the first and sixth waves.
Method
Prospective observational study of two cohorts of IMID patients diagnosed with COVID-19. First cohort March to May 2020, and second cohort December/2021 to February/2022.
Sociodemographic and clinical variables were collected and, in the second cohort, COVID-19 vaccination status. Statistical analysis established differences in characteristics and clinical course between the two cohorts.
Results
In total, 1627 patients were followed up, of whom 77 (4.60%) contracted COVID-19 during the first wave and 184 in the sixth wave (11.3%). In the sixth wave, there were fewer hospitalisations, intensive care unit admissions, and deaths than in the first wave (p = .000) and 180 patients (97.8%) had at least one dose of vaccine.
Conclusion
Early detection and vaccination have prevented the occurrence of serious complications.
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