虚弱对裂孔疝修补术的影响:一项全国性的住院临床和医疗利用结果分析。

Y Lee, B Huo, T McKechnie, J Agzarian, D Hong
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引用次数: 0

摘要

先前的研究建议采用观望的方法进行食管旁疝(PEH)修复,因为死亡风险增加。虽然当代研究表明选择性手术是安全有效的,但许多PEH患者都是老年人。因此,我们评估了在接受PEH修复的患者中,虚弱对住院结果和医疗利用率的影响。这项基于人群的回顾性队列研究评估了2015年10月至2019年12月期间接受PEH修复的国家住院患者样本数据库中的患者。收集人口统计学和围手术期数据,并使用11项改良虚弱指数测量虚弱程度。测量的结果包括住院死亡率、并发症、出院处置和医疗利用率。总的来说,10716名接受PEH修复的患者被确认,其中包括1442名虚弱的患者。与健壮的患者相比,虚弱的患者不太常见于女性,更常见于收入最低的四分之一人群。虚弱患者住院死亡率的几率更大[比值比(OR)2.83(95%CI 1.65-4.83);P
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of frailty on hiatal hernia repair: a nationwide analysis of in-hospital clinical and healthcare utilization outcomes.

Previous studies recommend a watch-and-wait approach to paraesophageal hernia (PEH) repair due to an increased risk for mortality. While contemporary studies suggest that elective surgery is safe and effective, many patients presenting with PEH are elderly. Therefore, we assessed the impact of frailty on in-hospital outcomes and healthcare utilization among patients receiving PEH repair. This retrospective population-based cohort study assessed patients from the National Inpatient Sample database who received PEH repair between October 2015 to December 2019. Demographic and perioperative data were gathered, and frailty was measured using the 11-item modified frailty index. The outcomes measured were in-hospital mortality, complications, discharge disposition, and healthcare utilization. Overall, 10,716 patients receiving PEH repair were identified, including 1442 frail patients. Frail patients were less often female and were more often in the lowest income quartile compared to robust patients. Frail patients were at greater odds for in-hospital mortality [odds ratio (OR) 2.83 (95% CI 1.65-4.83); P < 0.001], postoperative ICU admissions [OR 2.07 (95% CI 1.55-2.78); P < 0.001], any complications [OR 2.18 (95% CI 1.55-2.78); P < 0.001], hospital length of stay [mean difference (MD) 1.75 days (95% CI 1.30-2.210; P < 0.001], and total admission costs [MD $5631.65 (95% CI $3300.06-$7.963.24); P < 0.001] relative to their robust patients. While PEH repair in elderly patients is safe and effective, frail patients have an increased rate of in-hospital mortality, postoperative ICU admissions, complications, and total admission costs. Clinicians should consider patient frailty when identifying the most appropriate surgical candidates for PEH repair.

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