Langerhans cell histiocytosis located in the spheno-orbital bone and the pons: illustrative case.

Background: This is a case of aggressive Langerhans cell histiocytosis (LCH) with an atypical intracranial location.

Observations: In this report, the authors present the diagnosis and treatment of a 12-year-old male patient diagnosed with LCH. The patient was admitted to the emergency department with left-sided facial palsy, and a solid lesion with mass effect in the pons was found. A biopsy was performed via suboccipital craniotomy, and the diagnosis was LCH. A chemotherapy regimen was started since the LCH sample was the resistant type. The patient showed improvement in his neurological deficit following treatment.

Lessons: This rare localized and aggressive case's diagnosis process and treatment choices may apply to future cases.