一项为期12个月的随机对照试验测试了糖尿病预防项目群体生活方式平衡(DPP-GLB)对中风后人群(GLB-CVA)的疗效。

IF 3.6 2区 心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY
Simon Driver, Evan McShan, Chad Swank, Stephanie Calhoun, Megan Douglas, Alexandria Suhalka, Monica Bennett, Librada Callender, Christa Ochoa, Sridevi Mukkamala, Kaye Kramer
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引用次数: 0

摘要

背景:卒中经历与糖尿病和代谢综合征的风险增加有关,但针对人群独特需求的干预措施很少。目的:通过一项随机对照试验,检验卒中后个体糖尿病预防计划群体生活方式平衡计划(DPP-GLB)修改后的依从性和有效性。方法:研究对象为18-85岁、脑卒中后12个月体重指数≥25 kg/m2的成人。65人被分配到GLB-CVA干预组或6个月的等候名单对照组。参与者完成了为期12个月的GLB-CVA干预,并在基线、3、6和12个月收集了体重、人体测量、生物标志物、功能和患者报告的结果数据。结果:高出勤率(90%)和饮食和活动跟踪(71%)表明12个月GLB-CVA的高依从性。六个月的随机对照试验数据显示,与等候名单对照组(0.1±10.1磅,0%)相比,GLB-CVA组(7.4±13.6磅,3.65%)的体重显著减轻(p = 0.005),臂围(p = 0.04)、高密度脂蛋白(HDL)胆固醇(p = 0.028)、8年糖尿病风险(p = 0.011)和疼痛干扰(p < 0.001)均有改善。12个月的综合数据显示,参与者减轻了10.1±16.8磅(4.88%),腰围(p = 0.001)、糖化血红蛋白(3.6%)、舒张压(p < 0.001)、疼痛(p = 0.001)、社会参与(p = 0.025)、饮食习惯(p = 0.01)和习惯(p < 0.001)得到改善。结论:参与GLB-CVA可以导致中风后超重或肥胖个体的体重减轻和健康改善。未来的工作应该检查在现实环境中的有效性,并将重点放在知识翻译工作上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Results of a 12-Month Randomized Controlled Trial Testing the Efficacy of the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) for People Post Stroke (GLB-CVA).

Background: Experience of stroke is associated with an increased risk for diabetes and metabolic syndrome, yet few interventions exist that have been tailored to the population's unique needs.

Purpose: To examine adherence and efficacy of the Diabetes Prevention Program Group Lifestyle Balance program (DPP-GLB) modified for individuals post stroke (GLB-CVA) using a randomized controlled trial.

Methods: Adults (18-85 years of age), >12 months post stroke, and body mass index ≥25 kg/m2 were included in this study. Sixty-five individuals were assigned to either the GLB-CVA intervention or a 6-month wait-list control. Participants completed the 12-month GLB-CVA intervention, with attendance and assessment of weight, anthropometric, biomarker, functional, and patient reported outcome data collected at baseline, 3, 6, and 12 months.

Results: High attendance (90%) and dietary and activity tracking (71%) suggest high adherence to the 12-month GLB-CVA. Six-month randomized controlled trial data indicate significant weight loss (p = .005) in the GLB-CVA group (7.4 ± 13.6 lbs, 3.65%) compared with the wait-list control (0.1 ± 10.1 lbs, 0%), and improvements in arm circumference (p = .04), high-density lipoprotein (HDL) cholesterol (p = .028), 8-year diabetes risk (p = .011), and pain interference (p < .001). Combined 12-month data showed participants lost 10.1 ± 16.8 lbs (4.88%) and improved waist circumference (p = .001), HbA1c (3.6%), diastolic blood pressure (p < .001), pain (p = .001), social participation (p = .025), and eating practices (p = .01) and habits (p < .001).

Conclusions: Engagement in the GLB-CVA can result in weight loss and improved health for individuals who are overweight or obese following stroke. Future efforts should examine effectiveness in real-world settings and focus on knowledge translation efforts.

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来源期刊
Annals of Behavioral Medicine
Annals of Behavioral Medicine PSYCHOLOGY, MULTIDISCIPLINARY-
CiteScore
7.00
自引率
5.30%
发文量
65
期刊介绍: Annals of Behavioral Medicine aims to foster the exchange of knowledge derived from the disciplines involved in the field of behavioral medicine, and the integration of biological, psychosocial, and behavioral factors and principles as they relate to such areas as health promotion, disease prevention, risk factor modification, disease progression, adjustment and adaptation to physical disorders, and rehabilitation. To achieve these goals, much of the journal is devoted to the publication of original empirical articles including reports of randomized controlled trials, observational studies, or other basic and clinical investigations. Integrative reviews of the evidence for the application of behavioral interventions in health care will also be provided. .
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