伊拉克巴士拉献血者中输血传播感染的流行和趋势。

IF 3.3 Q2 GASTROENTEROLOGY & HEPATOLOGY
Khairallah A S Mohammed, Maha M Hameed, Abdullah H Mousa, Amar T Saleh
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引用次数: 0

摘要

背景:尽管输血挽救了数百万人的生命,但输血传播感染(tti)仍然威胁着需要输血的患者的生命。因此,对献血者进行筛查并研究献血者中感染性传播疾病的流行情况,可能会显示出这些疾病在我国人口中的负担。本研究的目的是评估2019年至2021年伊拉克巴士拉献血者中输血传播感染的血清患病率,作为在伊拉克提供安全输血的基础。方法:2019年1月1日至2021年12月31日在伊拉克巴士拉血库进行横断面研究。采集样本197 898份,进行乙型肝炎表面抗原(HBsAg)、抗乙型肝炎核心病毒(HBc)、抗丙型肝炎病毒(HCV)和梅毒免疫筛查。结果:2019年、2020年、2021年病毒性肝炎血清阳性率分别为:乙型肝炎病毒(HBV)阳性率1.54%、1.45%、1.14%,呈明显下降趋势,分别下降26%;抗- hcv阳性率分别为0.14%、0.12%和0.11%,呈显著下降趋势,降幅为21.4%;梅毒感染率分别为0.38、0.47、0.36,呈明显下降趋势,降幅为5.3%。在HBV阳性献血者中,抗hbc阳性2503例(1.26%),抗hbc和HBsAg均阳性173例(0.0874)。结论:病毒性肝炎和梅毒的患病率在2019年至2021年期间呈稳步下降趋势,巴士拉的患病率远低于伊拉克其他地区和邻国。本研究表明,在筛选献血者时使用抗hbc检测的重要性。这些发现将有助于提高对tti流行病学的了解,并支持卫生当局控制血源性疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq.

Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq.

Background: Despite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these diseases among our population. The aim of this study was to assess the seroprevalence rates of transfusion transmitted infections among blood donors in Basra, Iraq from 2019 to 2021 as groundwork for providing safe blood transfusion in Iraq.

Methods: A cross-sectional study was carried out in the blood banks in Basra, Iraq from 1 January 2019 to 31 December 2021. A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.

Results: The prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.

Conclusion: Prevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. The importance of using the anti-HBc test in the screening of blood donors was indicated in this study. These findings would contribute in improving the understanding of TTIs epidemiology and supporting health authorities controlling bloodborne diseases.

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来源期刊
BMJ Open Gastroenterology
BMJ Open Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.90
自引率
3.20%
发文量
68
审稿时长
2 weeks
期刊介绍: BMJ Open Gastroenterology is an online-only, peer-reviewed, open access gastroenterology journal, dedicated to publishing high-quality medical research from all disciplines and therapeutic areas of gastroenterology. It is the open access companion journal of Gut and is co-owned by the British Society of Gastroenterology. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around continuous publication, publishing research online as soon as the article is ready.
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