血液透析患者血管通路类型与抑郁的关系

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-04-27 DOI:10.1111/hdi.13092

Ahmet Rıfkı Çora, Ersin Çelik

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引用次数: 0

摘要

血液透析是终末期肾病(ESKD)患者最常用的治疗方法，而动静脉瘘(AV)是首选的血管通路。我们研究的目的是调查血管通路类型和抑郁症之间的潜在联系。方法对180例维持性血液透析患者进行横断面调查。采用贝克抑郁量表评估抑郁程度。人口统计学因素、治疗细节和实验室值均来自医院病历。结果:52% (n = 93)的患者通过房室瘘进行透析，48% (n = 87)的患者通过隧道式套管导管进行透析。在性别(p = 0.266)、是否存在糖尿病、高血压或外周动脉疾病(p = 0.409, p = 0.323, p = 0.317;分别)。Beck抑郁量表评分大于14分(表明存在抑郁)的患者中，使用隧道套管导管透析的患者(61%)明显高于使用房室瘘透析的患者(36%)(p = 0.001)。我们发现采用隧道式套管导管进行血液透析的患者抑郁评分在统计学上较高。

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Association between vascular access type and depression in hemodialysis patients

Introduction

Hemodialysis is the most common treatment used for end-stage kidney disease (ESKD) patients and an arteriovenous fistula (AV) fistula is the preferred vascular access. The goal of our study was to investigate potential associations between vascular access type and depression.

Methods

This was a cross-sectional survey of 180 patients receiving maintenance hemodialysis. The Beck Depression Inventory was used to assess degree of depression. Demographic factors, treatment details, and laboratory values were obtained from the hospital medical record.

Findings

Fifty-two percent (n = 93) of the patients were being dialyzed using an AV fistula and 48% (n = 87) via a tunneled cuffed catheter. No significant differences were found between access type use in terms of gender (p = 0.266), presence of diabetes, hypertension, or peripheral artery disease (p = 0.409, p = 0.323, p = 0.317; respectively). The prevalence of Beck Depression Inventory scores greater than 14 (marking presence of depression) was significantly higher in the patients being dialyzed with a tunneled cuffed catheters (61%) compared to patients dialyzed with an AV fistula (36%) (p = 0.001).

Discussion

We found statistically higher depression scores among patients receiving hemodialysis with a tunneled cuffed catheter.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.