Isabel de Fátima Alvim Braga, Eliana Napoleão Cozendey-Silva, Laila Zelkcovicz Ertler, Thiago Gonçalves Dos Santos Martins, Sabrina da Silva Santos, Bruno de Avilla da Fonseca E Silva, Lia Roque Assumpção, William Waissmann
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Early Abortions and Congenital Malformations: A Comparison Between Agricultural and Nonagricultural Areas in the State of São Paulo/Brazil.
Introduction: Areas with higher agricultural production have higher rates of abortion and malformation, probable related to pesticides.
Objective: To compare the rates of early abortion and fetal malformation in agricultural and nonagricultural areas.
Method: A survey was carried out on fetal deaths in children weighing less than 500 g or gestational age less than 22 weeks and fetal malformations in live births.
Results: From 1996 to 2018, there was an increase in the rates of abortion and, albeit to a lesser extent, malformation. The areas of greater agricultural production have higher rates of fetal mortality and malformation than the others.
Conclusions: The study suggests that areas with higher use of pesticides have higher rates of abortion and fetal malformations than the others, requiring further observational studies, reducing confounders inherent to the ecological study.
期刊介绍：
Journal of Occupational and Environmental Medicine is an indispensable guide to good health in the workplace for physicians, nurses, and researchers alike. In-depth, clinically oriented research articles and technical reports keep occupational and environmental medicine specialists up-to-date on new medical developments in the prevention, diagnosis, and rehabilitation of environmentally induced conditions and work-related injuries and illnesses.
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