布比卡因用于矮小产妇剖宫产:一项回顾性病例对照研究。

Q3 Medicine
AANA journal Pub Date : 2023-06-01
Elizabeth M S Lange, Paloma Toledo, Jillian Stariha, Josephine LiMandri, Derek Morley, Heather C Nixon
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引用次数: 0

摘要

脊髓布比卡因用于剖宫产的ED50和ED95在文献中有很好的描述;然而,身材极端的孕妇被排除在外。矮小产妇指的是身高≤148 cm。这项回顾性的病例对照研究评估了10年间接受剖宫产的矮个子产妇和对照组的麻醉效果。女性的麻醉类型和身体质量指数相匹配。提取的数据包括患者人口统计、产科和麻醉信息。主要终点是鞘内布比卡因的剂量。分类资料比较采用卡方检验,连续资料比较采用t检验或Mann-Whitney U检验。对26名身材矮小的女性和52名对照组的数据进行了评估。矮小产妇腰麻布比卡因平均剂量9.8±1.0 mg (P = 0.002)。除了一名身材矮小的患者外,所有患者都达到了足够的手术水平;没有高度脊髓阻滞的病例。对于身材矮小的产妇,通过减少脊髓布比卡因的剂量,可以获得足够的手术麻醉,而不会增加不良后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bupivacaine Dosing for Cesarean Delivery in Parturients of Short Stature: A Retrospective Case-Control Study.

The ED50 and ED95 of spinal bupivacaine for cesarean delivery has been well described in the literature; however, parturients with extremes of stature have been excluded. Parturients of short stature are a height of ≤ 148 cm. This retrospective, case-control study evaluated anesthetic outcomes for parturients of short stature and controls who underwent cesarean delivery over a 10-year period. Women were matched for anesthetic type and body mass index. Data extracted included patient demographics and obstetric and anesthetic information. The primary outcome was dose of intrathecal bupivacaine. Categorical data were compared using a chi-squared test, continuous data were compared using a t-test or Mann-Whitney U test. Data for 26 women of short stature and 52 controls were evaluated. The mean dose of bupivacaine used for spinal anesthesia in parturients of short stature was 9.8 ± 1.0 mg (P <.0001). The mean intrathecal bupivacaine dose used in combined spinal epidural anesthesia was 10.5 mg (interquartile range, 9-10.9) in parturients of short stature (P = .002). All but one patient of short stature achieved an adequate surgical level; there were no instances of high spinal blockade. Adequate surgical anesthesia was achieved with reduced dosing of spinal bupivacaine in parturients of short stature without an increase in adverse outcomes.

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来源期刊
AANA journal
AANA journal Medicine-Medicine (all)
CiteScore
1.20
自引率
0.00%
发文量
60
期刊介绍: Founded in 1931 and located in Park Ridge, Ill., the AANA is the professional organization for more than 90 percent of the nation’s nurse anesthetists. As advanced practice nurses, CRNAs administer approximately 32 million anesthetics in the United States each year. CRNAs practice in every setting where anesthesia is available and are the sole anesthesia providers in more than two-thirds of all rural hospitals. They administer every type of anesthetic, and provide care for every type of surgery or procedure, from open heart to cataract to pain management.
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