实体癌转移性股骨肿瘤引起的即将发生的病理性骨折与已完成的病理性骨折之间的髓内钉临床效果比较。

IF 1.5 4区 医学 Q3 ORTHOPEDICS
Sho Yanagisawa, Yoshiyasu Uchiyama, Yoshikazu Tanzawa, Takuya Watanabe, Shiho Wasai, Takehisa Suzuki, Masahiko Watanabe
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引用次数: 0

摘要

背景我们研究了转移性股骨肿瘤患者(不包括血液恶性肿瘤患者)髓内钉的治疗效果:我们对接受预防性手术与病理骨折后接受手术的患者进行了髓内钉治疗效果的回顾性评估。接受预防性手术(Mirels评分≥8分)的患者被分配到即将骨折组(n = 11),而在病理骨折后接受手术的患者被分配到已完成骨折组(n = 20):结果:即将骨折组的手术时间明显短于完全骨折组。即将骨折组的中位失血量明显少于完全骨折组,中位住院时间也明显短于完全骨折组。在手术后死亡的患者中,即将骨折组的术后中位存活时间明显长于完全骨折组。骨折即将愈合组恢复行走功能的患者明显多于骨折已愈合组。在并发症方面,完成骨折组有一名患者发生了感染。两组患者均未发现植入物损坏:结论:与完全骨折组相比,接受髓内钉治疗的骨折预兆组转移性股骨肿瘤患者的术后生存率和步态功能更好,失血量更少,手术和住院时间更短。这些研究结果表明了早期诊断和治疗的重要性以及在骨折发生前进行治疗的价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of the clinical outcomes of intramedullary nailing between impending and completed pathological fractures caused by metastatic femoral tumors from solid cancers

Background

We examined the treatment outcomes following intramedullary nailing in patients with metastatic femoral tumors, excluding those from hematological malignancies.

Methods

We retrospectively evaluated treatment outcomes following intramedullary nailing between patients who underwent preventative surgery compared with those who had surgery following pathological fracture. Patients who underwent preventative surgery (Mirels’ score ≥8) were allocated to the impending fracture group (n = 11) and those who underwent surgery after pathological fracture were allocated to the completed fracture group (n = 20).

Results

Duration of surgery was significantly shorter in the impending fracture group than in the completed fracture group. Median blood loss was significantly less, and the median duration of hospital stay was significantly shorter in the impending fracture group than in the completed fracture group. Among patients who died following surgery, the median postoperative survival duration was significantly longer in the impending fracture group than in the completed fracture group. Significantly more patients regained walking function in the impending fracture group than in the completed fracture group. Regarding complications, infection occurred in one patient in the completed fracture group. No implant damage was observed in either group.

Conclusions

Patients with metastatic femoral tumors who underwent intramedullary nailing in the impending fracture group had better postoperative survival and gait function, less blood loss, and shorter durations of surgery and hospital stay than those in the completed fracture group. These findings indicate the importance of early diagnosis and treatment and value of treatment prior to fracture occurrence.

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来源期刊
Journal of Orthopaedic Science
Journal of Orthopaedic Science 医学-整形外科
CiteScore
3.00
自引率
0.00%
发文量
290
审稿时长
90 days
期刊介绍: The Journal of Orthopaedic Science is the official peer-reviewed journal of the Japanese Orthopaedic Association. The journal publishes the latest researches and topical debates in all fields of clinical and experimental orthopaedics, including musculoskeletal medicine, sports medicine, locomotive syndrome, trauma, paediatrics, oncology and biomaterials, as well as basic researches.
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