Elena Zelikovna Golukhova, Inessa Viktorovna Slivneva, Inga Yur'evna Farulova, Ivan Ivanovich Skopin, Damir Ildarovich Marapov, Dar'ya Vladimirovna Murysova, Yuliya Dmitrievna Pirushkina, Irina Vasilyevna Volkovskaya
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In 25 cases, low gradients were identified from the apical window not corresponding to the visual structural changes in the aortic valve, or disagreement between the velocity and calculated parameters was detected. Patients were divided into two groups: concordant AS (<i>n</i> = 56; 71.8%) and discordant AS (<i>n</i> = 22; 28.2%). Three individuals were excluded from the discordant AS group due to the presence of moderate stenosis.</p><p><strong>Results: </strong>Based on the comparative analysis of transvalvular flow velocities obtained from multiposition scanning, the concordance group showed agreement between the velocity and calculated parameters. We observed an increase in the mean transvalvular pressure gradient (ΔP<sub>mean</sub>) and peak aortic jet velocity (V<sub>max</sub>), ΔP<sub>mean</sub> in 95.5% of patients, velocity time integral of transvalvular flow (VTI AV) in 90.9% of patients, and a decrease in aortic valve area (AVA) and indexed AVA in 90.9% of patients after applying RPW in all patients with discordant AS. The use of RPW allowed the reclassification of AS severity from discordant to concordant high-gradient AS in 88% of low-gradient AS cases.</p><p><strong>Conclusion: </strong>Underestimation of flow velocity and overestimation of AVA using the apical window may lead to misclassification of AS. 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The reproducibility feasibility of the right parasternal window (RPW) was 75.0% (<i>n</i> = 78). The mean age of the patients was 64 years, and 40 (51.3%) were female. In 25 cases, low gradients were identified from the apical window not corresponding to the visual structural changes in the aortic valve, or disagreement between the velocity and calculated parameters was detected. Patients were divided into two groups: concordant AS (<i>n</i> = 56; 71.8%) and discordant AS (<i>n</i> = 22; 28.2%). Three individuals were excluded from the discordant AS group due to the presence of moderate stenosis.</p><p><strong>Results: </strong>Based on the comparative analysis of transvalvular flow velocities obtained from multiposition scanning, the concordance group showed agreement between the velocity and calculated parameters. 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引用次数: 0
摘要
研究目的本研究旨在对使用多位置扫描和标准心尖窗评估主动脉瓣狭窄(AS)不一致的严重程度进行比较分析:所有患者(104 人)均在术前接受了经胸超声心动图(TTE)检查,并根据 AS 的严重程度进行排序。右胸骨旁窗(RPW)的再现性为 75.0%(78 人)。患者的平均年龄为64岁,其中40人(51.3%)为女性。在 25 例患者中,从心尖窗发现的低梯度与主动脉瓣的直观结构变化不符,或发现速度参数与计算参数不一致。患者被分为两组:一致的强直性脊柱炎(n = 56;71.8%)和不一致的强直性脊柱炎(n = 22;28.2%)。不一致强直性脊柱炎组中有三人因存在中度狭窄而被排除在外:根据对多位置扫描获得的跨瓣血流速度的比较分析,一致组的血流速度与计算参数一致。在对所有不一致的强直性脊柱炎患者应用 RPW 后,我们观察到平均跨瓣压力梯度(ΔPmean)和主动脉喷射速度峰值(Vmax)、ΔPmean 在 95.5% 的患者中增加,跨瓣血流速度时间积分(VTI AV)在 90.9% 的患者中增加,主动脉瓣面积(AVA)和指数化 AVA 在 90.9% 的患者中减少。在88%的低梯度AS病例中,使用RPW可将AS严重程度从不一致性重新分类为一致的高梯度AS:结论:使用心尖窗低估血流速度和高估AVA可能会导致AS分类错误。使用 RPW 有助于将 AS 的严重程度与流速特征相匹配,并减少低梯度 AS 病例的数量。
Advantages of Multiposition Scanning in Echocardiographic Assessment of the Severity of Discordant Aortic Stenosis.
Aim of the study: The aim of this study was to perform a comparative analysis of severity of discordant aortic stenosis (AS) assessment using multiposition scanning and the standard apical window.
Materials and methods: All patients (n = 104) underwent preoperative transthoracic echocardiography (TTE) and were ranked according to the degree of AS severity. The reproducibility feasibility of the right parasternal window (RPW) was 75.0% (n = 78). The mean age of the patients was 64 years, and 40 (51.3%) were female. In 25 cases, low gradients were identified from the apical window not corresponding to the visual structural changes in the aortic valve, or disagreement between the velocity and calculated parameters was detected. Patients were divided into two groups: concordant AS (n = 56; 71.8%) and discordant AS (n = 22; 28.2%). Three individuals were excluded from the discordant AS group due to the presence of moderate stenosis.
Results: Based on the comparative analysis of transvalvular flow velocities obtained from multiposition scanning, the concordance group showed agreement between the velocity and calculated parameters. We observed an increase in the mean transvalvular pressure gradient (ΔPmean) and peak aortic jet velocity (Vmax), ΔPmean in 95.5% of patients, velocity time integral of transvalvular flow (VTI AV) in 90.9% of patients, and a decrease in aortic valve area (AVA) and indexed AVA in 90.9% of patients after applying RPW in all patients with discordant AS. The use of RPW allowed the reclassification of AS severity from discordant to concordant high-gradient AS in 88% of low-gradient AS cases.
Conclusion: Underestimation of flow velocity and overestimation of AVA using the apical window may lead to misclassification of AS. The use of RPW helps to match the degree of AS severity with the velocity characteristics and reduce the number of low-gradient AS cases.
期刊介绍:
Pathophysiology is an international journal which publishes papers in English which address the etiology, development, and elimination of pathological processes. Contributions on the basic mechanisms underlying these processes, model systems and interdisciplinary approaches are strongly encouraged.